Ultrasound Assisted One-pot Synthesis of Dihydropyrimidinones Using Holmium Chloride As Catalyst

ultrasound assisted one-pot synthesis of dihydropyrimidinones using holmium chloride as catalyst

a simple and green chemical procedure was reported for the synthesis of dihydropyrimidinones from various aldehydes, ethyl acetoacetate and urea or thiourea using  holmium chloride as catalyst. the reactions were performed under solvent free conditions with ultrasound irradiation as the energy source. the advantages of this protocol include the excellent yield, operational simplicity, short tim...

Ultrasound based method for one-pot synthesis of substituted imidazoles using SiO2-OSbCl2 as highly effective and reusable catalyst

A simple highly versatile and efficient sonochemical synthesis of 1,2,4,5-tetrasubstituted and 2,4,5-trisubstituted imidazoles is achieved by condensation of 1,2-dicarbonyl compound, aldehyde, ammonium acetate and primary amine using antimony trichloride immobilized on silica gel (SiO2-OSbCl2) as a catalyst in ethanol at moderate temperature. Operational simplicity, practicability and applicabi...

Ultrasound based method for one-pot synthesis of substituted imidazoles using SiO2-OSbCl2 as highly effective and reusable catalyst

A simple highly versatile and efficient sonochemical synthesis of 1,2,4,5-tetrasubstituted and 2,4,5-trisubstituted imidazoles is achieved by condensation of 1,2-dicarbonyl compound, aldehyde, ammonium acetate and primary amine using antimony trichloride immobilized on silica gel (SiO2-OSbCl2) as a catalyst in ethanol at moderate temperature. Operational simplicity, practicability and applicabi...

CuCl2 Catalyzed Solvent-free One Pot Synthesis of Dihydropyrimidinones

One-Pot Multi-Component Synthesis of Dihydropyrimidinones via Biginelli Condensation

Three-component reactions have emerged as useful methods because the combinationof three components to generate new products in a single step is extremely economical,among the multi-component reactions. A green, simple, efficient, and cost-effective procedure has been carried out by the synthesis of dihydropyrimidinonesin Biginelli’s condensation of ethyl cyanoacetate, aldehyde and urea or thio...

Novel One-Pot Synthesis of Pyrazolopyranopyrimidinones Using Newly Produced γ-Alumina Nanoparticles as Powerful Catalyst

g-Alumina nanoparticles (g-Al2O3 NPs) were prepared via a new and simple synthetic route and characterized by field emission scanning electron microscopy, X-ray diffraction, and Fourier transform infrared spectroscopy. The catalytic activity of prepared g-Al2O3 NPs was investigated for the new one-pot, ...